Is tramadol associated to bleeding peptic ulcer? A nationwide case-control study in hospitalized Swedish patients.

<h4>Aims</h4>Tramadol, a widely used analgesic drug, inhibits the reuptake of noradrenaline and serotonin impairing the aggregation function of thrombocytes. However, the risk for severe bleeding has previously not been studied. The aim of the present study is to investigate the associat...

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Bibliographic Details
Main Authors: Hans Järnbert-Pettersson, Marine L Andersson, Katarina Bilén, Olle Broström, Jonatan D Lindh, Buster Mannheimer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0215356