Unveiling the Mechanism of Action of 7α-acetoxy-6β-hydroxyroyleanone on an MRSA/VISA Strain: Membrane and Cell Wall Interactions

Unveiling the Mechanism of Action of 7α-acetoxy-6β-hydroxyroyleanone on an MRSA/VISA Strain: Membrane and Cell Wall Interactions

The number of cases of failure in the treatment of infections associated with resistant bacteria is on the rise, due to the decreasing efficacy of current antibiotics. Notably, 7α-Acetoxy-6β-hydroxyroyleanone (AHR), a diterpene isolated from different <i>Plectranthus</i> species, showed...

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Bibliographic Details
Main Authors: Filipe Pereira, Teresa Figueiredo, Rodrigo F. M. de Almeida, Catarina A. C. Antunes, Catarina Garcia, Catarina P. Reis, Lia Ascensão, Rita G. Sobral, Patricia Rijo
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Biomolecules
Subjects:
7α-Acetoxy-6β-hydroxyroyleanone
MRSA
antibacterial activity
membrane interaction
cell wall
Online Access:https://www.mdpi.com/2218-273X/10/7/983

Internet

https://www.mdpi.com/2218-273X/10/7/983

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