Levothyroxine to increase live births in euthyroid women with thyroid antibodies trying to conceive: the TABLET RCT

Levothyroxine to increase live births in euthyroid women with thyroid antibodies trying to conceive: the TABLET RCT

Background: Thyroid autoantibodies, specifically thyroid peroxidase antibodies, have been associated with miscarriage and pre-term birth in women with a normal thyroid function. Small randomised controlled trials have found that treatment with levothyroxine may reduce such adverse outcomes in pregna...

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Main Authors: Rima K Dhillon-Smith, Lee J Middleton, Kirandeep K Sunner, Versha Cheed, Krys Baker, Samantha Farrell-Carver, Ruth Bender-Atik, Rina Agrawal, Kalsang Bhatia, Edmond Edi-Osagie, Tarek Ghobara, Pratima Gupta, Davor Jurkovic, Yacoub Khalaf, Marjory MacLean, Chris McCabe, Khashia Mulbagal, Natalie Nunes, Caroline Overton, Siobhan Quenby, Rajendra Rai, Nick Raine-Fenning, Lynne Robinson, Jackie Ross, Andrew Sizer, Rachel Small, Alex Tan, Martyn Underwood, Mark D Kilby, Kristien Boelaert, Jane Daniels, Shakila Thangaratinam, Shiao-Yng Chan, Arri Coomarasamy
Format: Article
Language:English
Published: NIHR Journals Library 2019-10-01
Series:Efficacy and Mechanism Evaluation
Subjects:
EUTHYROID
THYROID PEROXIDASE (TPO) ANTIBODIES
MISCARRIAGE
INFERTILITY
LEVOTHYROXINE
LIVE BIRTH
Online Access:https://doi.org/10.3310/eme06110

Internet

https://doi.org/10.3310/eme06110

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