Rates of switching antiretroviral drugs in a primary care service in South Africa before and after introduction of tenofovir.

Antiretroviral changes (single drug substitutions and regimen switches) limit treatment options and introduce challenges such as increased cost, monitoring and adherence difficulties. Patterns of drug substitutions and regimen switches from stavudine (d4T) and zidovudine (AZT) regimens have been wel...

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Bibliographic Details
Main Authors: Christine Njuguna, Catherine Orrell, Richard Kaplan, Linda-Gail Bekker, Robin Wood, Stephen D Lawn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3661537?pdf=render