IVGTT-based simple assessment of glucose tolerance in the Zucker fatty rat: Validation against minimal models.

For the assessment of glucose tolerance from IVGTT data in Zucker rat, minimal model methodology is reliable but time- and money-consuming. This study aimed to validate for the first time in Zucker rat, simple surrogate indexes of insulin sensitivity and secretion against the glucose-minimal-model i...

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Bibliographic Details
Main Authors: Micaela Morettini, Emanuela Faelli, Luisa Perasso, Sandro Fioretti, Laura Burattini, Piero Ruggeri, Francesco Di Nardo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5338807?pdf=render