Gametes deficient for Pot1 telomere binding proteins alter levels of telomeric foci for multiple generations

Lister-Shimauchi et al. find that gametes from mutants that lack the genes encoding telomere binding proteins POT-1 or POT-2 affect the levels of POT1 telomere foci in progeny, in opposite ways, for multiple generations and that gametes deficient in heterochromatin formation reduce POT1 foci. These...

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Bibliographic Details
Main Authors: Evan H. Lister-Shimauchi, Michael Dinh, Paul Maddox, Shawn Ahmed
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-020-01624-7