Modulation of nucleosomal DNA accessibility via charge-altering post-translational modifications in histone core

Abstract Background Controlled modulation of nucleosomal DNA accessibility via post-translational modifications (PTM) is a critical component to many cellular functions. Charge-altering PTMs in the globular histone core—including acetylation, phosphorylation, crotonylation, propionylation, butyrylat...

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Bibliographic Details
Main Authors: Andrew T. Fenley, Ramu Anandakrishnan, Yared H. Kidane, Alexey V. Onufriev
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Epigenetics & Chromatin
Online Access:http://link.springer.com/article/10.1186/s13072-018-0181-5