Understanding the causes and implications of endothelial metabolic variation in cardiovascular disease through genome scale metabolic modeling

Understanding the causes and implications of endothelial metabolic variation in cardiovascular disease through genome scale metabolic modeling

High-throughput biochemical profiling has led to a requirement for advanced data interpretation techniques capable of integrating the analysis of gene, protein, and metabolic profiles to shed light on genotype-phenotype relationships. Herein, we consider the current state of knowledge of endothelial...

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Bibliographic Details
Main Authors: Sarah eMcGarrity, Haraldur eHalldórsson, Sirus ePalsson, Pӓr Ingemar Johansson, Óttar eRolfsson
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Endothelium
Genetics
Metabolism
Metabolomics
metabolic modeling
personalized/precision medicine
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcvm.2016.00010/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcvm.2016.00010/full

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