Vitexin Mitigates Myocardial Ischemia/Reperfusion Injury in Rats by Regulating Mitochondrial Dysfunction via Epac1-Rap1 Signaling

Revascularization is an effective therapy for rescuing myocardial tissue after ischemic events. However, the process of reperfusion can lead to more severe cardiomyocyte damage, called myocardial ischemia-reperfusion (I/R) injury (MIRI). We have previously shown that vitexin (VT) (a flavonoid compou...

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Bibliographic Details
Main Authors: Huanhua Yang, Wei Xue, Caijuan Ding, Cheng Wang, Bohan Xu, Shuo Chen, Binshan Zha, Yuqian Sun, Huaqin Zhu, Junyan Zhang, Liuyi Dong
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2021/9921982