Physiological levels of nitrate support anoxic growth by denitrification of Pseudomonas aeruginosa at growth rates reported in cystic fibrosis lungs and sputum

Chronic Pseudomonas aeruginosa lung infection is the most severe complication in patients with cystic fibrosis (CF). The infection is characterised by the formation of biofilm surrounded by numerous polymorphonuclear leukocytes (PMNs) and strong O2 depletion in the endobronchial mucus. We have repor...

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Bibliographic Details
Main Authors: Laura eLine, Morten eAlhede, Mette eKolpen, Michael eKühl, Oana eCiofu, Thomas eBjarnsholt, Claus eMoser, Masanori eToyofuku, Nobuhiko eNomura, Niels eHøiby, Peter Østrup Jensen
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2014.00554/full