New Potent 5α- Reductase and Aromatase Inhibitors Derived from 1,2,3-Triazole Derivative

New Potent 5α- Reductase and Aromatase Inhibitors Derived from 1,2,3-Triazole Derivative

This work describes the utility of pyrazole-4-carbaldehyde <b>1</b> as starting material for the synthesis of a novel potent series of 5&#945;-reductase and aromatase inhibitors derived from 1,2,3-triazole derivative. Condensation of <b>1</b> with active methylene and dif...

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Bibliographic Details
Main Authors: Mohamed El-Naggar, Amira S. Abd El-All, Shweekar I. A. El-Naem, Mohamed M. Abdalla, Huda R. M. Rashdan
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Molecules
Subjects:
1,2,3-triazoles
5-α reductase inhibitors
aromatase inhibitors
hormone-dependent cancer
Online Access:https://www.mdpi.com/1420-3049/25/3/672

Internet

https://www.mdpi.com/1420-3049/25/3/672

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