The CXCR4-Dependent LASP1-Ago2 Interaction in Triple-Negative Breast Cancer

The CXCR4-Dependent LASP1-Ago2 Interaction in Triple-Negative Breast Cancer

The CXCR4-LASP1 axis is an emerging target in the field of breast cancer metastasis. C-X-C chemokine receptor type 4 (CXCR4) mediates directed cell migration when activated by its cognate ligand CXCL12. LIM and SH3 Protein 1 (LASP1) is a critical node in the CXCR4 signaling pathway, as its deficienc...

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Bibliographic Details
Main Authors: Augustus M. C. Tilley, Cory M. Howard, Sangita Sridharan, Boopathi Subramaniyan, Nicole R. Bearss, Sawsan Alkhalili, Dayanidhi Raman
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cancers
Subjects:
Argonaute2
LASP1
CXCR4
Let-7a
triple negative breast cancer
Online Access:https://www.mdpi.com/2072-6694/12/9/2455

Internet

https://www.mdpi.com/2072-6694/12/9/2455

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