ELL2 Is Downregulated and Associated with Galactose-Deficient IgA1 in IgA Nephropathy

Background. Galactose-deficient IgA1 (Gd-IgA1) is an important causal factor in IgA nephropathy; however, the underlying mechanism for the production of Gd-IgA1 is unknown. The elongation factor for RNA polymerase II (ELL2), which encoded a key component of the superelongation complex (SEC), drives...

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Bibliographic Details
Main Authors: Youxia Liu, Jie Zheng, Na Zhao, Junya Jia, Tiekun Yan
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2019/2407067