ELL2 Is Downregulated and Associated with Galactose-Deficient IgA1 in IgA Nephropathy
Background. Galactose-deficient IgA1 (Gd-IgA1) is an important causal factor in IgA nephropathy; however, the underlying mechanism for the production of Gd-IgA1 is unknown. The elongation factor for RNA polymerase II (ELL2), which encoded a key component of the superelongation complex (SEC), drives...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2019-01-01
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Series: | Disease Markers |
Online Access: | http://dx.doi.org/10.1155/2019/2407067 |