Computational modeling of molecular dynamics of G41R mutant form of human tyrosyl-tRNA synthetase, assosiated with Charcot-Marie-Tooth neuropathy

Computational modeling of molecular dynamics of G41R mutant form of human tyrosyl-tRNA synthetase, assosiated with Charcot-Marie-Tooth neuropathy

The computational structural models of human tyrosyl-tRNA synthetase and its mutant form G41R (Charcot-Marie-Tooth associated) were constructed, while their whole structural coordinates are still unknown. Grid-services of MolDynGrid Virtual Labo­ratory and Ukrainian National Grid-infrastructure were...

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Bibliographic Details
Main Authors: O. V. Savytskyi, A. I. Kornelyuk
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine and Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine. 2015-12-01
Series:Ukrainian Biochemical Journal
Subjects:
Charcot-Marie-Tooth neuropathy
computer modeling
CP1 insertion
G41R
grid compu­ting
MolDynGrid
molecular dynamics
mutant form of tyrosyl-tRNA synthetase (HsTyrRS)
Online Access:http://ukrbiochemjournal.org/wp-content/uploads/2015/12/Savytskyi_6_15.pdf

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http://ukrbiochemjournal.org/wp-content/uploads/2015/12/Savytskyi_6_15.pdf

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