Transcriptional regulation of the tumor suppressor FHL2 by p53 in human kidney and liver cells.

Four and a Half LIM protein 2 (FHL2) is a LIM domain only protein that is able to form various protein complexes and regulate gene transcription. Recent findings showed that FHL2 is a potential tumor suppressor gene that was down-regulated in hepatocellular carcinoma (HCC). Moreover, FHL2 can bind t...

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Bibliographic Details
Main Authors: Jiaying Xu, Junwei Zhou, Man-Shan Li, Chor-Fung Ng, Yuen-Keng Ng, Paul Bo-San Lai, Stephen Kwok-Wing Tsui
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25121502/pdf/?tool=EBI