A diversity-generating retroelement encoded by a globally ubiquitous Bacteroides phage

Abstract Background Diversity-generating retroelements (DGRs) are genetic cassettes that selectively mutate target genes to produce hypervariable proteins. First characterized in Bordetella bacteriophage BPP-1, the DGR creates a hypervariable phage tail fiber that enables host tropism switching. Sub...

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Bibliographic Details
Main Authors: Sean Benler, Ana Georgina Cobián-Güemes, Katelyn McNair, Shr-Hau Hung, Kyle Levi, Rob Edwards, Forest Rohwer
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Microbiome
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40168-018-0573-6