A diversity-generating retroelement encoded by a globally ubiquitous Bacteroides phage
Abstract Background Diversity-generating retroelements (DGRs) are genetic cassettes that selectively mutate target genes to produce hypervariable proteins. First characterized in Bordetella bacteriophage BPP-1, the DGR creates a hypervariable phage tail fiber that enables host tropism switching. Sub...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-10-01
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Series: | Microbiome |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s40168-018-0573-6 |