Performance of risk prediction for inflammatory bowel disease based on genotyping platform and genomic risk score method

Performance of risk prediction for inflammatory bowel disease based on genotyping platform and genomic risk score method

Abstract Background Predicting risk of disease from genotypes is being increasingly proposed for a variety of diagnostic and prognostic purposes. Genome-wide association studies (GWAS) have identified a large number of genome-wide significant susceptibility loci for Crohn’s disease (CD) and ulcerati...

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Bibliographic Details
Main Authors: Guo-Bo Chen, Sang Hong Lee, Grant W. Montgomery, Naomi R. Wray, Peter M. Visscher, Richard B. Gearry, Ian C. Lawrance, Jane M. Andrews, Peter Bampton, Gillian Mahy, Sally Bell, Alissa Walsh, Susan Connor, Miles Sparrow, Lisa M. Bowdler, Lisa A. Simms, Krupa Krishnaprasad, the International IBD Genetics Consortium, Graham L. Radford-Smith, Gerhard Moser
Format: Article
Language:English
Published: BMC 2017-08-01
Series:BMC Medical Genetics
Subjects:
Inflammatory bowel disease
Crohn’s disease
Ulcerative colitis
Case-control study
Risk score
SNP array
Online Access:http://link.springer.com/article/10.1186/s12881-017-0451-2

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http://link.springer.com/article/10.1186/s12881-017-0451-2

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