Crosstalk between beta‐adrenergic and insulin signaling mediates mechanistic target of rapamycin hyperactivation in liver of high‐fat diet‐fed male mice

Crosstalk between beta‐adrenergic and insulin signaling mediates mechanistic target of rapamycin hyperactivation in liver of high‐fat diet‐fed male mice

Abstract Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease. While increased nutrient intake and sympathetic activity have been associated with the disease, the pathogenesis of NAFLD remains incompletely understood. We investigated the impact of the interactio...

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Bibliographic Details
Main Authors: Sadia Ashraf, Nadia Ashraf, Gizem Yilmaz, Romain Harmancey
Format: Article
Language:English
Published: Wiley 2021-07-01
Series:Physiological Reports
Subjects:
fatty liver
glycogen
high‐fat diet
insulin
sympathetic nervous system
Online Access:https://doi.org/10.14814/phy2.14958

Internet

https://doi.org/10.14814/phy2.14958

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