Cardiac troponin I autoantibody induces myocardial dysfunction by PTEN signaling activationResearch in context

Background: The objective of the current study was to study the molecular mechanism(s) underlying cardiac troponin I autoantibody (cTnIAAb) binding to cardiomyocyte and resultant myocardial damage/dysfunction. Methods: cTnIAAb was purified from serum of 10 acute myocardial infarction (AMI) patients...

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Bibliographic Details
Main Authors: Yu Wu, Yang-hua Qin, Yang Liu, Li Zhu, Xian-xian Zhao, Yao-yang Liu, Shi-wen Luo, Gu-sheng Tang, Qian Shen
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419305675