MUNC18–1 gene abnormalities are involved in neurodevelopmental disorders through defective cortical architecture during brain development

MUNC18–1 gene abnormalities are involved in neurodevelopmental disorders through defective cortical architecture during brain development

Abstract While Munc18–1 interacts with Syntaxin1 and controls the formation of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNARE) complex to regulate presynaptic vesicle fusion in developed neurons, this molecule is likely to be involved in brain development since its gen...

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Bibliographic Details
Main Authors: Nanako Hamada, Ikuko Iwamoto, Hidenori Tabata, Koh-ichi Nagata
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Acta Neuropathologica Communications
Subjects:
Munc18–1
Syntaxin1A
Corticogenesis
Neurodevelopmental disorders
Online Access:http://link.springer.com/article/10.1186/s40478-017-0498-5

Internet

http://link.springer.com/article/10.1186/s40478-017-0498-5

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