Detection of the Vascular Endothelial Growth Factor with a Novel Bioluminescence Resonance Energy Transfer Pair Using a Two-Component System

In this paper we describe a two-component BRET (bioluminescence resonance energy transfer)-based method to detect vascular endothelial growth factor (VEGF) molecules in unknown samples as the basis for subsequent in vivo use. A luminescent VEGF binding molecule, which binds in the receptor binding m...

Full description

Bibliographic Details
Main Authors: Tobias Wimmer, Eva Schroeter, Birgit Lorenz, Knut Stieger
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/17/1/145