Prevascularization promotes endogenous cell-mediated angiogenesis by upregulating the expression of fibrinogen and connective tissue growth factor in tissue-engineered bone grafts

Prevascularization promotes endogenous cell-mediated angiogenesis by upregulating the expression of fibrinogen and connective tissue growth factor in tissue-engineered bone grafts

Abstract Background Vascularization is one of the most important processes in tissue-engineered bone graft (TEBG)-mediated regeneration of large segmental bone defects. We previously showed that prevascularization of TEBGs promoted capillary vessel formation within the defected site and accelerated...

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Bibliographic Details
Main Authors: Pengzhen Cheng, Donglin Li, Yi Gao, Tianqing Cao, Huijie Jiang, Jimeng Wang, Junqin Li, Shuaishuai Zhang, Yue Song, Bin Liu, Chunmei Wang, Liu Yang, Guoxian Pei
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Stem Cell Research & Therapy
Subjects:
Prevascularization
Angiogenesis
Tissue-engineered bone grafts
Fibrinogen
Connective tissue growth factor
Online Access:http://link.springer.com/article/10.1186/s13287-018-0925-y

Internet

http://link.springer.com/article/10.1186/s13287-018-0925-y

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