Cost-effectiveness of cascade genetic testing for familial hypercholesterolemia in the United States: A simulation analysis

Cost-effectiveness of cascade genetic testing for familial hypercholesterolemia in the United States: A simulation analysis

Objective There is no coordinated cascade testing program for familial hypercholesterolemia (FH) in the U.S. We evaluated the contemporary cost-effectiveness of cascade genetic testing relatives of FH probands with a pathogenic variant.Methods A simulation model was created to simulate multiple fami...

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Bibliographic Details
Main Authors: Candace L. Jackson, Todd Huschka, Bijan Borah, Katherine Agre, Magdi Zordok, Medhat Farwati, James Moriarty, Iftikhar J. Kullo
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:American Journal of Preventive Cardiology
Subjects:
Familial hypercholesterolemia
Prevention
Genetic testing
Cascade testing
Online Access:http://www.sciencedirect.com/science/article/pii/S2666667721001008

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http://www.sciencedirect.com/science/article/pii/S2666667721001008

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