Allelic drop-out may occur with a primer binding site polymorphism for the commonly used RFLP assay for the -1131T>C polymorphism of the <it>Apolipoprotein AV </it>gene

<p>Abstract</p> <p><it>Apolipoprotein AV (ApoAV) </it>gene variant, -1131T>C, is associated with increased triglyceride concentrations in all ethnic groups studied. An <it>MseI </it>based RFLP analysis is the most commonly used method for genotyping this...

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Bibliographic Details
Main Authors: Hattersley Andrew T, Frayling Timothy M, Yajnik Chittaranjan S, Ellard Sian, Ward Kirsten J, Venigalla Prathyusha NS, Chandak Giriraj R
Format: Article
Language:English
Published: BMC 2006-05-01
Series:Lipids in Health and Disease
Online Access:http://www.lipidworld.com/content/5/1/11