The Citrus Flavonoid Naringenin Protects the Myocardium from Ageing-Dependent Dysfunction: Potential Role of SIRT1

Sirtuin 1 (SIRT1) enzyme plays a pivotal role in the regulation of many physiological functions. In particular, it is implicated in ageing-related diseases, such as cardiac hypertrophy, myocardial infarct, and endothelial dysfunction; moreover, its expression decreases with age. Therefore, an effect...

Full description

Bibliographic Details
Main Authors: Lara Testai, Eugenia Piragine, Ilaria Piano, Lorenzo Flori, Eleonora Da Pozzo, Vincenzo Miragliotta, Andrea Pirone, Valentina Citi, Lorenzo Di Cesare Mannelli, Simone Brogi, Sara Carpi, Alma Martelli, Paola Nieri, Claudia Martini, Carla Ghelardini, Claudia Gargini, Vincenzo Calderone
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2020/4650207