Functional limitations of plasmacytoid dendritic cells limit type I interferon, T cell responses and virus control in early life.

Functional limitations of plasmacytoid dendritic cells limit type I interferon, T cell responses and virus control in early life.

Infant mortality from viral infection remains a major global health concern: viruses causing acute infections in immunologically mature hosts often follow a more severe course in early life, with prolonged or persistent viral replication. Similarly, the WE strain of lymphocytic choriomeningitis viru...

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Bibliographic Details
Main Authors: Elodie Belnoue, Paola Fontannaz, Anne-Françoise Rochat, Chantal Tougne, Andreas Bergthaler, Paul-Henri Lambert, Daniel D Pinschewer, Claire-Anne Siegrist
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3871569?pdf=render

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http://europepmc.org/articles/PMC3871569?pdf=render

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