Genome-wide screen reveals important roles for ESCRT proteins in drug/ion resistance of fission yeast.

Genome-wide screen reveals important roles for ESCRT proteins in drug/ion resistance of fission yeast.

To study sodium homeostasis, we performed a genome-wide screen for deletion strains that show resistance to NaCl. We identified 34 NaCl-resistant strains. Among them, the largest group that consists of 10 genes related to membrane trafficking and 7 out of 10 genes are ESCRT proteins which are involv...

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Bibliographic Details
Main Authors: Yikun Yang, Qiannan Liu, Guanglie Jiang, Si Chen, Lina Zhou, Norihiro Sakamoto, Takayoshi Kuno, Yue Fang, Fan Yao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5983419?pdf=render

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http://europepmc.org/articles/PMC5983419?pdf=render

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