Spatial regulation and the rate of signal transduction activation.

Of the many important signaling events that take place on the surface of a mammalian cell, activation of signal transduction pathways via interactions of cell surface receptors is one of the most important. Evidence suggests that cell surface proteins are not as freely diffusible as implied by the c...

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Bibliographic Details
Main Authors: Nizar N Batada, Larry A Shepp, David O Siegmund, Michael Levitt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-05-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC1458967?pdf=render