Conformations and cryo-force spectroscopy of spray-deposited single-strand DNA on gold
Cryo-electron microscopy can determine the structure but not the nanomechanics of biological matter. Here the authors combine force spectroscopy in cryogenic conditions with computer simulations to characterize the properties of DNA simultaneously down to the sub-nm level.
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-02-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-08531-4 |