Exosomes: composition, biogenesis, and mechanisms in cancer metastasis and drug resistance

Abstract Tumor-derived exosomes (TDEs) participate in formation and progression of different cancer processes, including tumor microenvironment (TME) remodeling, angiogenesis, invasion, metastasis and drug-resistance. Exosomes initiate or suppress various signaling pathways in the recipient cells vi...

Full description

Bibliographic Details
Main Authors: Ladan Mashouri, Hassan Yousefi, Amir Reza Aref, Ali mohammad Ahadi, Fatemeh Molaei, Suresh K. Alahari
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Molecular Cancer
Online Access:http://link.springer.com/article/10.1186/s12943-019-0991-5