Synthetic Genetic Targeting of Genome Instability in Cancer
Cancer is a leading cause of death throughout the World. A limitation of many current chemotherapeutic approaches is that their cytotoxic effects are not restricted to cancer cells, and adverse side effects can occur within normal tissues. Consequently, novel strategies are urgently needed to better...
Main Authors: | Kirk J. McManus, Brent J. Guppy, Babu V. Sajesh |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2013-06-01
|
Series: | Cancers |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6694/5/3/739 |
Similar Items
-
Computational Approaches to Identify Genetic Interactions for Cancer Therapeutics
by: Benstead-Hume Graeme, et al.
Published: (2017-09-01) -
Evidence that synthetic lethality underlies the mutual exclusivity of oncogenic KRAS and EGFR mutations in lung adenocarcinoma
by: Arun M Unni, et al.
Published: (2015-06-01) -
Synthetic Lethality in Lung Cancer—From the Perspective of Cancer Genomics
by: Iwao Shimomura, et al.
Published: (2019-03-01) -
Human papillomavirus and genome instability: from productive infection to cancer
by: Bruna Prati, et al.
Published: (2018-09-01) -
Evolving Therapeutic Strategies to Exploit Chromosome Instability in Cancer
by: Laura L. Thompson, et al.
Published: (2017-11-01)