CD4+T Cells: Differentiation and Functions

CD4+T cells are crucial in achieving a regulated effective immune response to pathogens. Naive CD4+T cells are activated after interaction with antigen-MHC complex and differentiate into specific subtypes depending mainly on the cytokine milieu of the microenvironment. Besides the classical T-helper...

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Bibliographic Details
Main Authors: Rishi Vishal Luckheeram, Rui Zhou, Asha Devi Verma, Bing Xia
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2012/925135