ASK1 modulates the expression of microRNA Let7A in microglia under high glucose in vitro condition

Hyperglycemia results in oxidative stress and leads to neuronal apoptosis in the brain. Diabetes studies show that microglia participate in the progression of neuropathogenesis through their involvement in inflammation in vivo and in vitro. In high-glucose-induced inflammation, apoptosis signal regu...

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Bibliographic Details
Main Authors: Juhyun eSong, Jong Eun eLee
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00198/full