A detailed map of coupled circadian clock and cell cycle with qualitative dynamics validation

Abstract Background The temporal coordination of biological processes by the circadian clock is an important mechanism, and its disruption has negative health outcomes, including cancer. Experimental and theoretical evidence suggests that the oscillators driving the circadian clock and the cell cycl...

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Bibliographic Details
Main Authors: Adrien Rougny, Loïc Paulevé, Michèle Teboul, Franck Delaunay
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-021-04158-9