Knockdown of the cellular protein LRPPRC attenuates HIV-1 infection.

Knockdown of the cellular protein LRPPRC attenuates HIV-1 infection.

HIV-1 exploits numerous host cellular pathways for productive infection. To identify novel factors involved in HIV-1 replication, HIV-1 integrase and matrix protein complexes were captured at 4 hours post infection for proteomic analysis using an affinity purification system. Leucine-rich PPR-motif...

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Bibliographic Details
Main Authors: Cameron J Schweitzer, John M Matthews, Christian J Madson, Meghan R Donnellan, Ronald L Cerny, Michael Belshan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3395635?pdf=render

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http://europepmc.org/articles/PMC3395635?pdf=render

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