The Discovery of RNA Aptamers that Selectively Bind Glioblastoma Stem Cells

Glioblastoma (GBM) is the most aggressive primary brain tumor in adults. Despite progress in surgical and medical neuro-oncology, prognosis for GBM patients remains dismal, with a median survival of only 14–15 months. The modest benefit of conventional therapies is due to the presence of GBM stem ce...

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Bibliographic Details
Main Authors: Alessandra Affinito, Cristina Quintavalle, Carla Lucia Esposito, Giuseppina Roscigno, Claudia Vilardo, Silvia Nuzzo, Lucia Ricci-Vitiani, Gabriele De Luca, Roberto Pallini, Anna S. Kichkailo, Ivan N. Lapin, Vittorio de Franciscis, Gerolama Condorelli
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Molecular Therapy: Nucleic Acids
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253119302288