Novel elvitegravir nanoformulation approach to suppress the viral load in HIV-infected macrophages

Novel elvitegravir nanoformulation approach to suppress the viral load in HIV-infected macrophages

Purpose: Monocytes serve as sanctuary sites for HIV-1 from which virus is difficult to be eliminated. Therefore, an effective viral suppression in monocytes is critical for effective antiretroviral therapy (ART). This study focuses on a new strategy using nanoformulation to optimize the efficacy of...

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Bibliographic Details
Main Authors: Yuqing Gong, Pallabita Chowdhury, Narasimha M. Midde, Mohammad A. Rahman, Murali M. Yallapu, Santosh Kumar
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Biochemistry and Biophysics Reports
Subjects:
PLGA nanoparticles
Antiretroviral therapy
Elvitegravir
HIV
Monocytes
Drug delivery systems
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580817302145

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http://www.sciencedirect.com/science/article/pii/S2405580817302145

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