Cellular dynamics of EMT: lessons from live in vivo imaging of embryonic development

Cellular dynamics of EMT: lessons from live in vivo imaging of embryonic development

Abstract Epithelial-mesenchymal transition (EMT) refers to a process in which epithelial cells lose apical-basal polarity and loosen cell–cell junctions to take on mesenchymal cell morphologies and invasive properties that facilitate migration through extracellular matrix. EMT—and the reverse mesenc...

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Bibliographic Details
Main Author: Jeffrey D. Amack
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Cell Communication and Signaling
Subjects:
Epithelial-mesenchymal transition (EMT)
Mesenchymal-epithelial transition (MET)
Cell migration
Cancer metastasis
Actin cytoskeleton
In vivo live imaging
Online Access:https://doi.org/10.1186/s12964-021-00761-8

Internet

https://doi.org/10.1186/s12964-021-00761-8

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