The myeloid receptor PILRβ mediates the balance of inflammatory responses through regulation of IL-27 production.

The myeloid receptor PILRβ mediates the balance of inflammatory responses through regulation of IL-27 production.

Paired immunoglobulin-like receptors beta, PILRβ, and alpha, PILRα, are related to the Siglec family of receptors and are expressed primarily on cells of the myeloid lineage. PILRβ is a DAP12 binding partner expressed on both human and mouse myeloid cells. The potential ligand, CD99, is found on man...

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Bibliographic Details
Main Authors: Cristina M Tato, Barbara Joyce-Shaikh, Antara Banerjee, Yi Chen, Manjiri Sathe, Sarah E Ewald, Man-Ru Liu, Daniel Gorman, Terrill K McClanahan, Joseph H Phillips, Paul G Heyworth, Daniel J Cua
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3313972?pdf=render

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http://europepmc.org/articles/PMC3313972?pdf=render

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