Detection of low abundance RNA molecules in individual cells by flow cytometry.

A variety of RNA analysis technologies are available for the detection of RNA transcripts from bulk cell populations. However, the techniques for RNA detection from individual cells have been limited. Here we adapt a novel in situ signal amplification method (the RNAScope® detection platform) for th...

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Bibliographic Details
Main Authors: Mary Beth Hanley, Woodrow Lomas, Dev Mittar, Vernon Maino, Emily Park
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3575505?pdf=render