Management of Neuroinflammatory Responses to AAV-Mediated Gene Therapies for Neurodegenerative Diseases

Management of Neuroinflammatory Responses to AAV-Mediated Gene Therapies for Neurodegenerative Diseases

Recently, adeno-associated virus (AAV)-mediated gene therapies have attracted clinical interest for treating neurodegenerative diseases including spinal muscular atrophy (SMA), Canavan disease (CD), Parkinson’s disease (PD), and Friedreich’s ataxia (FA). The influx of clinical fi...

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Bibliographic Details
Main Authors: Barbara A. Perez, Alison Shutterly, Ying Kai Chan, Barry J. Byrne, Manuela Corti
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Brain Sciences
Subjects:
aav
gene therapy
neurodegeneration
neuroinflammation
immunosuppression
Online Access:https://www.mdpi.com/2076-3425/10/2/119

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https://www.mdpi.com/2076-3425/10/2/119

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