Genetic screen identifies a requirement for SMN in mRNA localisation within the Drosophila oocyte

Genetic screen identifies a requirement for SMN in mRNA localisation within the Drosophila oocyte

Abstract Objective Spinal muscular atrophy (SMA) results from insufficient levels of the survival motor neuron (SMN) protein. Drosophila is conducive to large-scale genetic-modifier screens which can reveal novel pathways underpinning the disease mechanism. We tested the ability of a large collectio...

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Bibliographic Details
Main Authors: Beppe Aquilina, Ruben J. Cauchi
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Research Notes
Subjects:
Survival motor neuron
SMN
Genetic screen
Spinal muscular atrophy
mRNA localisation
Gurken
Online Access:http://link.springer.com/article/10.1186/s13104-018-3496-1

Internet

http://link.springer.com/article/10.1186/s13104-018-3496-1

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