Dysregulation of glutathione synthesis in liver disease
Glutathione (GSH), a tripeptide that is present in all mammalian tissues, is especially highly concentrated in the liver. GSH synthesis occurs via two adenosine triphosphate (ATP)-requiring enzymatic steps: the first is rate-limiting, catalyzed by glutamate-cysteine ligase, generates γ-glutamylcyste...
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| Format: | Article |
| Language: | English |
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KeAi Communications Co., Ltd.
2020-06-01
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| Series: | Liver Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2542568420300234 |