Diagnostic criteria for the Brugada syndrome: Can they be improved?

Introduction: Diagnosis of Brugada syndrome (BS) currently requires documentation of a characteristic repolarization pattern (type 1 Brugada ECG). Mutations in the SCN5A gene, which codes for sodium channel NaV 1.5, are found in 38% of familial cases of BS. Sodium current dysfunction negatively affe...

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Bibliographic Details
Main Authors: Luís Ferreira Santos, Telmo Pereira, Bruno Rodrigues, Emanuel Correia, Davide Moreira, Luís Nunes, António Costa, Luís Elvas, José Carlos Machado, Sérgio Castedo, Carla Henriques, Ana Matos, Oliveira Santos
Format: Article
Language:English
Published: Elsevier 2012-05-01
Series:Revista Portuguesa de Cardiologia (English Edition)
Online Access:http://www.sciencedirect.com/science/article/pii/S2174204912000384