hUCMSC-extracellular vesicles downregulated hepatic stellate cell activation and reduced liver injury in S. japonicum-infected mice

hUCMSC-extracellular vesicles downregulated hepatic stellate cell activation and reduced liver injury in S. japonicum-infected mice

Abstract Background Accumulating evidence shows that mesenchymal stem cells (MSCs) have the potential as a cellular therapy avenue for schistosome-induced liver injury. Extracellular vesicles (EVs) are membranous vesicles released by almost all cell types, and EVs produced by MSCs (MSC-EVs) exert th...

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Bibliographic Details
Main Authors: Liyang Dong, Yanan Pu, Xiaojun Chen, Xin Qi, Lina Zhang, Lei Xu, Wei Li, Yongbin Ma, Sha Zhou, Jifeng Zhu, Yalin Li, Xuefeng Wang, Chuan Su
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Stem Cell Research & Therapy
Subjects:
Human umbilical cord mesenchymal stem cells
Extracellular vesicles
Schistosomiasis
Liver injury
Online Access:https://doi.org/10.1186/s13287-019-1539-8

Internet

https://doi.org/10.1186/s13287-019-1539-8

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