Bovine Delta Papillomavirus E5 Oncoprotein Interacts With TRIM25 and Hampers Antiviral Innate Immune Response Mediated by RIG-I-Like Receptors

Bovine Delta Papillomavirus E5 Oncoprotein Interacts With TRIM25 and Hampers Antiviral Innate Immune Response Mediated by RIG-I-Like Receptors

Persistent infection and tumourigenesis by papillomaviruses (PVs) require viral manipulation of various of cellular processes, including those involved in innate immune responses. Herein, we showed that bovine PV (BPV) E5 oncoprotein interacts with a tripartite motif-containing 25 (TRIM25) but not w...

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Bibliographic Details
Main Authors: Francesca De Falco, Anna Cutarelli, Ivan Gentile, Pellegrino Cerino, Valeria Uleri, Adriana Florinela Catoi, Sante Roperto
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Immunology
Subjects:
bovine papilloma virus E5 oncoprotein
tripartite motif containing 25 (TRIM25)
retinoic acid-inducible gene I (RIG-I)
mitochondrial antiviral-signalling (MAVS) protein
melanoma differentiation-associated gene 5 (MDA5)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.658762/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.658762/full

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