Attenuation of everolimus-induced cytotoxicity by a protective autophagic pathway involving ERK activation in renal cell carcinoma cells

Yizhou Zeng, Xiaofang Tian, Quan Wang, Weiyang He, Jing Fan, Xin Gou Department of Urinary Surgery, The First Affiliated Hospital of Chongqing Medical University, Yuzhong District, Chongqing, China Aim: The mammalian target of rapamycin (mTOR) pathway is a critical target for cancer treatment and...

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Bibliographic Details
Main Authors: Zeng YZ, Tian XF, Wang Q, He WY, Fan J, Gou X
Format: Article
Language:English
Published: Dove Medical Press 2018-04-01
Series:Drug Design, Development and Therapy
Subjects:
ERK
Online Access:https://www.dovepress.com/attenuation-of-everolimus-induced-cytotoxicity-by-a-protective-autopha-peer-reviewed-article-DDDT