Low-mutation-rate, reduced-genome <it>Escherichia coli</it>: an improved host for faithful maintenance of engineered genetic constructs
<p>Abstract</p> <p>Background</p> <p>Molecular mechanisms generating genetic variation provide the basis for evolution and long-term survival of a population in a changing environment. In stable, laboratory conditions, the variation-generating mechanisms are dispensable...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-01-01
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Series: | Microbial Cell Factories |
Subjects: | |
Online Access: | http://www.microbialcellfactories.com/content/11/1/11 |