Ciliated neurons lining the central canal sense both fluid movement and pH through ASIC3

Cerebrospinal fluid-contacting (CSF-c) cells line the central canal of the vertebrate spinal cord yet their function remains unknown. Here, Javaland et al. show that CSF-c neurons in the lamprey respond to mechanical stimulation and lowered pH, effects likely mediated by ASIC3-channels.

Bibliographic Details
Main Authors: Elham Jalalvand, Brita Robertson, Peter Wallén, Sten Grillner
Format: Article
Language:English
Published: Nature Publishing Group 2016-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms10002