Cryopreserved clumps of mesenchymal stem cell/extracellular matrix complexes retain osteogenic capacity and induce bone regeneration

Cryopreserved clumps of mesenchymal stem cell/extracellular matrix complexes retain osteogenic capacity and induce bone regeneration

Abstract Background Three-dimensional (3D) cultured clumps of mesenchymal stem cell (MSC)/extracellular matrix (ECM) complexes (C-MSCs) consist of cells and self-produced ECM. C-MSCs can regulate cellular functions in vitro and can be grafted into a defect site without an artificial scaffold to indu...

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Bibliographic Details
Main Authors: Souta Motoike, Mikihito Kajiya, Nao Komatsu, Manabu Takewaki, Susumu Horikoshi, Shinji Matsuda, Kazuhisa Ouhara, Tomoyuki Iwata, Katsuhiro Takeda, Tsuyoshi Fujita, Hidemi Kurihara
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Stem Cell Research & Therapy
Subjects:
Artificial scaffold free
Bone regeneration
Cryopreservation
C-MSC
MSCs
Online Access:http://link.springer.com/article/10.1186/s13287-018-0826-0

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http://link.springer.com/article/10.1186/s13287-018-0826-0

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